Onsite Generating Solutions

Generate Your Own Nitrogen for all LC/MS/MS Instruments

Many LC/MS/MS Instruments are now available and each of these requires a different nitrogen gas specification to meet its specific nitrogen gas flow. A range of dedicated Nitrogen Generators specifically developed to meet individual manufacturers nitrogen requirements is now available.

These LC/MS/MS instruments can use anywhere for a single unit from 6 L/min to in excess of 30 L/min at ATP (Atmospheric Test Pressure) and often operate over 24 hour timeframes. Ensuring that there is a constant supply of gas to these instruments can create many challenges and the gas consumption over a short time period can be beyond the scope of cylinder supply. The alternative to traditional gas supply (cylinders, dewars or liquid nitrogen tanks) is the installation of a gas generator.

On Site Generating Solutions is able to offer a Nitrogen Generator that is specific and tailored to each individual instruments gas flow rate needs, purity and outlet pressures. These units have been tested by the instrument manufacturers themselves and satisfy all the needs for a consistent and pure nitrogen gas supply. The range of nitrogen generating systems available are suitable for a single instrument up to multiple instruments and cover flow rates from as little as 6 L/min ATP to greater than 240 L/min.

There are two types of nitrogen generators that are suitable for LC/MS/MS applications, that is either Membrane Technology or Pressure Swing Adsorption (PSA) technology and the choice of system depends mainly on the purity and flow rate required for the application. Many laboratories often run other instruments apart from the LC/MS/MS from the nitrogen generator supply and this effects the overall purity of gas required.

 

Nitrogen Generation by Membrane Technology

The membrane system consists mainly of parallel membrane modules, inside equipped with thousands of hollow fibres.

Compressed and purified air passes through these hollow fibres, which separate the oxygen molecules from air. Due to the different molecule diameters of the air gases, the oxygen molecules penetrate faster through the hollow fibres surface than the nitrogen molecules.

Nitrogen enriched gas leaves the hollow fibres as the gas produced. Mainly the flow velocity through the hollow fibres effects the remaining oxygen content.

PEAK Scientific Instruments manufacture the range of NM Series of Nitrogen Generators, which includes eleven (11) models each, of which are tailored to an individual manufacturers instruments gas flow rate, purity and outlet pressure. These units have been tested by the instrument manufacturers and satisfy all the needs for a consistent and pure nitrogen gas supply. The models available include:

Dedicated Nitrogen Systems for LC/MS/MS Analysers

Nitrogen Generators for LC/MS/ MS Instruments from PEAK Scientific Instruments
Model Flow Rate @ ATP Outlet Pressure Gas Purity Compressor Features
NM18L 18 L/min ATP 110 - 145 psi 7.6 bar Meets Purity Requirements
Of LC/MS/MS Instrument		 No - Connects To In House Air • Designed For Single MS Instruments
• Optional Oxygen Analyser With Alarm
• Wall Mountable
NM18LA 18 L/min ATP 110 - 145 psi 7.6 bar Meets Purity Requirements
Of LC/MS/MS Instrument		 Integral - Oil Less • Designed For Single MS Instruments
• Optional Oxygen Analyser With Alarm
• Wall Mountable
NM30LA 30 L/min ATP 100 psi 7 bar Meets Purity Requirements
Of LC/MS/MS Instrument		 Integral - Oil Less • Designed For Multiple MS Instruments
• Plug & Use System
• Wall Mountable
NM30L 30 L/min ATP Input Independent Meets Purity Requirements
Of LC/MS/MS Instrument		 No - Connects To In House Air • Designed For Multiple MS Instruments
• Wall Mountable
• Plug & Use System
NM60L 60 L/min ATP Input Independent Meets Purity Requirements
Of LC/MS/MS Instrument		 No - Connects To In House Air • Designed For Multiple LC/MS Instruments
NM120L 120 L/min ATP Input Independent Meets Purity Requirements
Of LC/MS/MS Instrument		 No - Connects To In House Air • Designed For Multiple LC/MS Instruments
NM180L 180 L/min ATP Input Independent Meets Purity Requirements
Of LC/MS/MS Instrument		 No - Connects To In House Air • Designed For Multiple LC/MS Instruments
NM240L 240 L/min ATP Input Independent Meets Purity Requirements
Of LC/MS/MS Instrument		 No - Connects To In House Air • Designed For Multiple LC/MS Instruments
NM300L 300 L/min ATP Input Independent Meets Purity Requirements
Of LC/MS/MS Instrument		 No - Connects To In House Air • Designed For Multiple LC/MS Instruments
NM360L 360 L/min ATP Input Independent Meets Purity Requirements
Of LC/MS/MS Instrument		 No - Connects To In House Air • Designed For Multiple LC/MS Instruments
NM420L 420 L/min ATP Input Independent Meets Purity Requirements
Of LC/MS/MS Instrument		 No - Connects To In House Air • Designed For Multiple LC/MS Instruments

Customer Information Kits for LC/MS/MS Analysers

For more information on above products: Customer Information Kit for LC/MS/MS Analysers.

 

Gas Station for API & LC/MS/MS Analysers from PEAK Scientific Instruments
Model Flow Rate N2 Flow Rate Air Outlet Pressure Notes
NM20ZA Curtain Gas (Nitrogen) 5L/min @ 60psi Source Gas (Zero Air) 22L/min
@ 100psi Exhaust Gas (Air) 8L/min @ 60psi 		System Set • Designed for LC/MS API analysers
• Mobile
• Plug & use system
• Three gas lines from 1 system
• Safety cut out feature
• Noise level 59 db(A)
N100DR 12 L/min N2 - Curtain Gas

26 L/min Zero Air -
Source Gas

8 L/min Air -
Exhaust Gas		 60 psi


100 psi


60 psi		 Meets API Purity Needs

• Integral - Oil Less
• Dual redundant Air Compressors
• Improved Reliability
• Integrated Self Diagnostics
• Mobile
• Quiet in Operation
A120DR 90 l/min

120 psi

 Meets API Purity Needs

• Quiet in Operation
• Uninterrupted supply of compressed air
• Mobile
• Improved Reliability
• Integrated Self Diagnosis
N300DR 12 L/min N2 - Curtain Gas

26 L/min Zero Air -
Source Gas

8 L/min Air -
Exhaust Gas		 60 psi


100 psi


60 psi

Meets API Purity Needs

• Integral - Oil Less
• Improved Reliability
• Integrated Self Diagnostics
• Mobile
• Quiet in Operation
A320DR

12 L/min N2 Curtain gas

26 L/min (Zero Air) Source Gas

8 L/min (Air) Exhaust Gas

60 psi


100 psi


60 psi

 Meets API Purity Needs

• Dual redundancy compressor
• Continuous service
NM20Z Curtain Gas (Nitrogen) 10L/min @ 60psi Source Gas (Zero Air) 22L/min
@ 100psi Exhaust Gas (Air) 8L/min @ 60psi 		110 - 130 psi • Configured for Positive Ion Mode of your API Analyser
• Wall Mountable
• Plug & use system
• Three gas lines from 1 system
• No electrical requirements

Customer Information Kits for LC/MS/MS Analysers

For more information on above products: Customer Information Kit for API & LC/MS/MS Analysers.

 

Nitrogen Generation by Pressure Swing Absorption (PSA)

The nitrogen generation plant based on the PSA-process consists of two adsorption towers filled with Carbon Molecular Sieve (CMS). Compressed and purified air is passed through the adsorption towers. Mainly Oxygen is adsorbed on the CMS and Nitrogen enriched gas leaves the tower. The oxygen concentration can be reduced to almost all required levels.

During adsorption in one tower the second tower is totally regenerated just by depressurisation to ambient pressure. The oxygen enriched off gas with 30 Ð 35% volume Oxygen content is vented to atmosphere. About one minute the adsorption in one adsorption tower the process controller switches over to the second tower and the first one is regenerated.

CarboTrade manufacture an extensive range of PSA nitrogen generators suitable for laboratory instrument applications, which are the Micro & GA range. The nitrogen generator is supplied mounted on a skid and requires an air supply. These can be supplied including refrigerated dryer, filters oil/water separator and buffer storage tanks.

Optional oxygen analysers are available and are supplied with two gauges and two safety settings (purity and air pressure) installed on the PSA control box.

 

GA Range Flow vs Purity - Nm3/hr

Nitrogen Flow Versus Purity Table of Generators Range from CarboTrade
N2 FLOW (Nm3hr) at stated % N2 Purity ATP
Flow
Nitrogen Purity
Air Required Nm3/hr
Nm3/hr
99.9995%
5ppm
99.999%
10ppm
99.995%
50ppm
99.99%
100ppm
MP 50
1.2
Prod. N2
0.04
0.05
0.09
0.13
MP 100
2.4
Prod. N2
0.08
0.1
0.18
0.27
MP 200
4.5
Prod. N2
0.16
0.2
0.36
0.54
Model
Flow
Nitrogen Purity
Nm3/hr
99.999%
99.99%
99.9%
99.5%
99%
98%
97%
95%
Micro 500
Prod.N2
0.1
0.2
0.3
0.5
0.6
0.8
0.9
1.1
Air 10 bar
0.8
1.1
1.6
1.9
2.1
2.3
2.6
2.9
Micro 1000
Prod.N2
0.1
0.3
0.5
0.9
1.1
1.4
1.6
1.9
Air 10 bar
1.4
1.9
2.6
3.1
3.5
3.9
4.4
5.0
Micro 2500
Prod.N2
0.3
0.7
1.4
2.2
2.7
3.5
4.0
4.9
Air 10 bar
3.6
4.9
6.7
8.1
9.0
10.1
11.3
12.7
Micro 4000
Prod.N2
0.5
1.1
2.2
3.5
4.4
5.6
6.5
7.9
Air 10 bar
5.8
7.9
10.8
12.9
14.4
16.2
18.1
20.4
Micro 5000
Prod.N2
0.6
1.3
2.7
4.3
5.3
6.8
7.9
9.6
4 towers
Air 10 bar
7.0
9.6
13.1
15.7
17.5
19.7
22.0
24.8
Micro 8000
Prod.N2
1.0
2.0
4.2
6.6
8.3
10.6
12.3
14.9
4 towers
Air 10 bar
11.0
14.9
20.5
24.6
27.4
30..8
34.4
38.8
GA 10 S
Prod.N2
1.9
4.0
8.2
13.1
15.9
20.5
23.3
27.8
Air 10 bar
19.9
27.1
36.0
43.1
46.1
53.2
55.9
61.3
GA 20 S
Prod.N2
3.2
6.6
13.6
21.7
26.4
34.0
38.7
46.2
Air 10 bar
33.0
44.9
59.8
71.6
76.6
88.3
92.9
101.7
GA 30 S
Prod.N2
4.0
8.2
16.9
27.1
32.9
42.4
48.2
57.7
Air 10 bar
41.2
56.0
74.5
89.3
95.5
110.1
115.8
126.8
GA 40 S
Prod.N2
5.5
11.2
23.1
37.0
45.0
57.8
65.9
78.7
Air 10 bar
56.3
76.5
101.8
122.0
130.5
150.4
158.1
173.2
GA 50 S
Prod.N2
6.9
14.3
29.3
46.8
57.0
73.3
83.5
99.8
Air 10 bar
71.3
96.9
129.0
154.6
165.4
190.6
200.4
219.5
GA 60 S
Prod.N2
8.2
16.9
34.8
55.5
67.6
86.9
99.0
118.3
Air 10 bar
84.5
114.9
152.9
183.2
196.0
225.9
237.5
260.2
GA 70 S
Prod.N2
9.2
18.9
39.0
62.2
75.8
97.4
110.9
132.6
Air 10 bar
94.8
128.8
171.5
205.4
219.7
253.3
266.3
291.7
GA 80 S
Prod.N2
11.3
23.2
47.7
76.1
92.7
119.1
135.7
162.2
Air 10 bar
115.9
157.5
209.7
251.2
268.7
309.8
325.7
356.8
GA 90 S
Prod.N2
12.1
25.0
51.3
82.0
99.8
128.3
146.2
174.7
Air 10 bar
124.8
169.7
225.9
270.6
289.5
333.7
350.8
384.3
GA 100 S
Prod.N2
13.0
26.7
54.9
87.7
106.8
137.3
156.4
186.9
Air 10 bar
133.6
181.6
241.7
289.5
309.7
357.0
375.3
411.2
GA 120 S
Prod.N2
16.7
34.4
70.8
113.0
137.6
176.9
201.5
240.8
Air 10 bar
172.1
234.0
311.4
373.1
399.1
460.1
483.6
529.8
GA 150 S
Prod.N2
19.9
41.0
84.3
134.6
163.9
210.7
239.9
286.8
Air 10 bar
204.9
278.6
370.8
444.2
475.2
547.8
575.8
630.9
GA 200 S
Prod.N2
26.7
55.1
113.3
180.9
220.3
283.2
322.5
385.5
Air 10 bar
275.5
374.5
498.4
597.1
638.8
736.3
774.1
848.0
GA 250 S
Prod.N2
33.9
69.8
143.7
229.5
279.4
359.2
409.1
488.9
Air 10 bar
349.4
474.9
632.2
757.3
810.2
933.9
981.8
1075.6
GA 300 S
Prod.N2
43.0
88.5
182.1
290.8
354.1
455.2
518.4
619.6
Air 10 bar
442.8
601.9
801.2
959.7
1026.8
1183.6
1244.3
1363.1
GA 400 S
Prod.N2
54.7
112.7
231.8
370.3
450.8
579.6
660.1
788.9
Air 10 bar
563.8
766.4
1020.1
1222.0
1307.4
1507.0
1584.3
1735.7
GA 500 S
Prod.N2
69.2
142.5
293.1
468.2
570.0
732.9
834.7
997.5
Air 10 bar
712.9
969.0
1289.9
1545.1
1653.0
1905.5
2003.2
2194.5

Please note: the flow shown is valid for 20degC ambient temperature. Correction factors must be applied for igh heat conditions.

GA Range Flow vs Purity - Litre/Minute

Nitrogen Flow Versus Purity Table of Generators Range from CarboTrade
N2 FLOW (litre/minute) at stated % N2 Purity ATP
Flow
Nitrogen Purity
Air Required
Litre/min
99.9995%
5ppm
99.999%
10ppm
99.995%
50ppm
99.99%
100ppm
MP 50
20 l/m
Prod. N2
0.67
0.83
1.50
2.17
MP 100
40 l/m
Prod. N2
1.33
1.67
3.00
4.50
MP 200
75 l/m
Prod. N2
2.67
3.33
6.00
9.00
Model
Flow
Nitrogen Purity
Nm3/hr
99.999%
99.99%
99.9%
99.5%
99%
98%
97%
95%
Micro 500
Prod.N2
1.3
2.5
5.3
8.3
10.5
13.3
15.5
18.8
Air 10 bar
13.8
18.8
25.8
31.0
34.5
38.8
43.3
49.0
Micro 1000
Prod.N2
2.1
4.2
9.0
14.2
17.7
22.7
26.2
31.8
Air 10 bar
23.4
31.8
43.7
52.3
58.3
65.7
73..3
82.8
Micro 2500
Prod.N2
5.4
10.8
22.8
36.3
45.3
58.0
67.2
81.7
Air 10 bar
60.0
81.7
112.0
134.2
149.7
168.3
188.0
212.2
Micro 4000
Prod.N2
8.8
17.5
36.7
58.2
72.7
93.2
107.7
130.8
Air 10 bar
96.2
130.8
179.7
215.0
240.0
270.0
301.7
340.0
Micro 5000
Prod.N2
10.6
21.2
44.7
70.8
88.5
113.3
131.0
159.3
4 towers
Air 10 bar
117.2
159.3
218.3
261.7
291.7
328.3
366.7
413.3
Micro 8000
Prod.N2
16.6
33.2
69.7
110.7
138.3
176.7
205.0
248.3
4 towers
Air 10 bar
182.6
248.3
341.7
410.0
456.7
513.3
573.3
646.7
GA 10 S
Prod.N2
32.2
66.3
136.4
217.9
265.2
341.0
388.4
464.1
Air 10 bar
331.7
450.9
600.2
719.0
769.2
886.6
932.1
1021.1
GA 20 S
Prod.N2
53.5
110.1
226.5
361.7
440.4
566.2
644.8
770.6
Air 10 bar
550.8
748.6
996.5
1193.7
1277.0
1472.1
1547.5
1695.4
GA 30 S
Prod.N2
66.7
137.3
282.4
451.0
549.1
705.9
804.0
960.8
Air 10 bar
686.7
933.4
1242.4
1488.3
1592.3
1835.4
1929.5
2113.9
GA 40 S
Prod.N2
91.1
187.5
3855.7
616.0
749.9
964.2
1098.1
1312.3
Air 10 bar
937.9
1274.8
1696.9
2032.8
2174.7
2506.8
2635.4
2887.1
GA 50 S
Prod.N2
115.4
237.6
488.8
780.7
950.4
1222.0
1391.7
1663.2
Air 10 bar
1188.7
1615.7
2150.6
2576.3
2756.2
3177.1
3340.0
3659.1
GA 60 S
Prod.N2
136.8
281.6
579.3
925.3
1126.4
1448.2
1649.4
1971.2
Air 10 bar
1408.8
1914.9
2548.9
3053.4
3266.6
3765.4
3958.5
4336.7
GA 70 S
Prod.N2
153.3
315.7
649.4
1037.3
1262.8
1623.6
1849.1
2209.9
Air 10 bar
1579.4
2146.8
2857.6
3423.1
3662.2
4221.4
4437.9
4861.8
GA 80 S
Prod.N2
187.5
386.1
794.3
1268.6
1544.4
1985.7
2261.5
2702.7
Air 10 bar
1931.6
2625.5
3494.8
4186.5
4478.8
5162.8
5427.5
5946.0
GA 90 S
Prod.N2
202.0
415.9
855.6
1366.6
1663.7
2139.1
2436.2
2911.5
Air 10 bar
2080.8
2828.3
3764.7
4509.8
4824.8
5561.6
5846.8
6405.3
GA 100 S
Prod.N2
216.1
445.0
915.4
1462.1
1779.9
2288.5
2606.3
3114.8
Air 10 bar
2226.2
3025.9
4027.7
4824.8
5161.7
5950.0
6255.1
6852.7
GA 120 S
Prod.N2
278.5
573.4
1179.6
1884.1
2293.7
2949.0
3358.6
4014.0
Air 10 bar
2868.8
3899.3
5190.3
6217.6
6651.7
7667.5
8060.7
8830.8
GA 150 S
Prod.N2
331.6
682.7
1404.5
2243.3
2731.0
3511.3
3999.0
4779.2
Air 10 bar
3415.7
4642.7
6179.9
7402.9
7919.9
9129.3
9597.5
10514.3
GA 200 S
Prod.N2
445.8
917.8
1888.0
3015.6
3671.2
4720.1
5375.6
6424.6
Air 10 bar
4591.6
6241.0
8307.3
9951.5
10646.4
12272.2
12901.6
14134.0
GA 250 S
Prod.N2
565.4
1164.1
2394.7
3824.8
4656.3
5986.7
6818.2
8148.6
Air 10 bar
5823.7
7915.8
10536.6
12622.0
13503.3
15565.4
16363.7
17926.9
GA 300 S
Prod.N2
716.5
1475.2
3034.8
4847.2
5901.0
7586.9
8640.7
10326.7
Air 10 bar
7380.4
10031.6
13353.0
15995.8
17112.8
19726.1
20737.7
22718.7
GA 400 S
Prod.N2
912.4
1878.4
3864.2
6171.9
7513.6
9660.4
11002.1
13148.9
Air 10 bar
9397.4
12773.2
17002.3
20367.3
21789.6
25117.0
26405.1
28927.5
GA 500 S
Prod.N2
1153.6
2375.0
4885.8
7803.7
9500.2
12214.5
13911.0
16625.3
Air 10 bar
11882.0
16150.3
21497.5
25752.3
27550.5
31757.7
33386.3
36575.7

Please note: the flow shown is valid for 20degC ambient temperature. Correction factors must be applied for high heat conditions.

Many Instruments and Applications such as: GC , LC, Autosamplers, LCMS, Evaporation, AA, CO2 Analysers, Emission Analysers, FT-IR, Lasers, NMR, Ozone Analysers, Rheometers, Robotic Systems, Thermal Analysers, Stack Gas Sampler, Total Hydrocarbon Analyser, Total Organic Carbon Analyser, Fumehoods, Carbon Analysers, Purging, Sparging, Pneumatics and more...all need pure, clean & dry gas and this can be provided by gas generators.

The gas generator range includes:Air Nitrogen GeneratorsCompressed Air Units for API LC/MS/MS & LC/MS/MSELSD Nitrogen GeneratorsHydrogenNitrogenNitrogen Generating PlantsNitrogen for LC/MS/MSGas Stations - Nitrogen Generators for API LC/MS/MSNitrogen for LCMS Complete RangeZero AirCalibration GasOzonePurge GasAPI LC/MS/MS Nitrogen Generator RangeTOC GasAir Dryers and PurifiersAutomatic Switch OverAir NitrogenGas Leak Detection

Additional References: Customer Information Kits for LC/MS/MS AnalysersCustomer Information Kits for API LC/MS/MS AnalysersTechnical Articles - GC ApplicationsTrouble Shooting Guides for GC ApplicationIndustrial Gas Generator Application SummaryLaboratory Gas Generator Application Summary

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15-19 Hillside Street, Bacchus Marsh, VIC. 3340
PO Box 754, Bacchus Marsh, VIC. 3340
Tel: 03 5367 8277
Fax: 03 5367 6477
Email: info@onsitegenerating.com